GASTRO-RETENTIVE FLOATING DRUG DELIVERY SYSTEM
Keywords:Gastro retentive, floating drug delivery system
The purpose of reviewing on Gastro-retentive floating drug delivery systems (GRDDS) was to compile the recent literature
with special focus on the aim, principal mechanism of floatation and to achieve gastric retention and to deliver ‘narrow
absorption window’ drugs. These reviews also focus on the various approaches used for the floating drug delivery systems.
The floating drug delivery system can remain in the gastric region for several hours via floating mechanism on the gastric
contents and hence significantly prolong the gastric residence time of the drugs. This review article is in pursuit of giving
detailed information on the design, classification, approaches, factors, In-vitro and In-vivo evaluation parameters,
advantages, disadvantages and the future potential of FDDS.
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