Elucidation of in vitro anti-inflammatory activity Of Achyranthes aspera (L.) By HRBC Membrane Stabilization Method

Authors

  • Thafshila Aafrin AM PG and Research Department of Biochemistry, Sengamala Thayaar Educational Trust Women’s College, Sundarakkottai, Mannargudi-614 016.
  • Anuradha, R PG and Research Department of Biochemistry, Sengamala Thayaar Educational Trust Women’s College, Sundarakkottai, Mannargudi-614 016.

Keywords:

Achyranthes aspera, HRBC, Diclofenac sodium, Anti-Inflammatory

Abstract

The whole plant extract of Achyranthes aspera were assessed for in vitro anti-inflammatory activity by HRBC membrane stabilization method. The presence of flavanoids has been reported earlier in Achyranthes aspera. Since the flavanoids have remarkable anti-inflammatory activity, so the present work aims at evaluating the       anti-inflammatory activity of Achyranthes aspera. Different concentrations (100,200, 300?g/ml) of extract were compared against standard Diclofenac sodium. Maximum stabilization in our study of aqueous extract is 98.85% and ethanolic extract is 98.95% at 300?g/ml. Therefore, our studies support the use of Achyranthes aspera in treating inflammation. Further investigations are anticipated to identify the active components and lead to their further clinical use.

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Published

2018-04-04
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Thafshila Aafrin AM, and Anuradha, R. “Elucidation of in Vitro Anti-Inflammatory Activity Of Achyranthes Aspera (L.) By HRBC Membrane Stabilization Method”. International Journal of Pharmaceutics and Drug Analysis, vol. 6, no. 4, Apr. 2018, pp. 435-8, https://ijpda.com/index.php/journal/article/view/394.

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