Review Of Ethnobotanical, Phytochemical And Pharmacological Profile Of Cardio-spermum halicacabum Linn.
Keywords:
Ethnobotanical, Cardiospermum halicacabum Linn., phytochemical and pharmacological profileAbstract
Cardiospermum halicacabum Linn. belonging to family Sapindaceae is an herbaceous plant, extensively dispersed in tropical and subtropical areas of world. Cardiospermum halicacabum Linn. is commonly known as “Balloon vine”. It is used for cough, hyperthermia, rheumatism, lumbago, nervous illnesses and amenorrhea. This plant is used in Ayurveda and folk medicine for the treatment of rheumatism, lumbago, earache and fever. The presence of flavones, aglycones, triterpenoids, glycosides, variety of fatty acids and volatile esters are confirmed by phytochemical screening. The plant possesses activities like antioxidant, antifungal, antiparasitic, antidiarrheal, anxiolytic, rubifacient, antipyretic and management of painful, arthritic inflammatory conditions. Therefore, the present reviews paper an attempt to compile an up-to-date and comprehensive review of Cardiospermum halicacabum Linn.that covers its Ethnobotanical, phytochemical, pharmacological data.
Downloads
References
Ahmed, I., Ahmed, M. and Ahmed, A. 1993. Chemical investigation of the genus Cardiospermum of the family sapindaceae. Lahore: Science International. 22: 286.
Al-Rehaily, A.J., El-Tahir, K.E.H., Mossa, J.S. and Rafatullah, S. 2001. Pharmacological studies of various extract from hexane extract of Ticleanobilis in rodents. at Prod Sci. 7: 76-82.
Asha, V.V. and Ushpangadan, P. 1999. Antipyretic activity of Cardiospermum halicacabum. Indian J. Exp. Biol. 37(4):411-414.
Bussmann, R.W. 2006. Ethnobotany of the Samburu of Mt. Nyiru, South Turkana, Kenya. Journal of Ethnobiology and Ethnomedicine. 2(35): 1746-4269.
Chopra, R.N., Nayar, S.L., and Chopra, I.C. 1956. Glossary of Indian Medicinal Plants. New Delhi: Council of Scientific and Industrial Research.
Dass, A.K. 1966. Chemical examination of Cardiospermum halicacabum L. Bulletin of Botanical Survey of India. 8: 357-358.
Di Carlo, G., Autore, G., Izzo, A.A., Maibline, P., Mascolo, N. and Viola, P. 1993. Inhibition of intestinal motility and secretion by flavonoids in mice and rats: structure- activity relationship. J Pharm Pharmacol. 45: 1054-1059.
Ferrara, I., Schettino, O. and Montesano, D. 1996.Triterpenoids from Cardiospermum halicacabum L. Phytotherapy Research. 10: 192-194.
Galvez, J., Zarzuelo, A., Crespo, M.E., Lorente, M.D., Ocete, M.A. and Jimenez, J.1993.Antidiarrhoeal activity of Euphorbia hirta extract and isolation of an active flavonoidal constituent. Planta Med. 59: 333-6.
Hopkins, C.Y., Ewing, D.F. and Chiosholm, M.J. 1968. A short chain ester from the seed oil of Cardio-spermum halicacabum Linn. Phytochemistry. 7: 619-624.
Jayabalan, N.,2006. Plant Biotechnology, APH Publishing Corporation, India. p. 214.
Jayanthi, G., Sathishkumar T., Senthilkumar, T. and Jegadeesan M. 2012. Essential oil from the seeds of Cardiospermum halicacabum L. var. Microcarpum. Asian J. Pharm. Biol. Res. 2(3):177-179.
Kirtikar, K.R., andBasu, B.D. 1935. Indian Medicinal Plants, pp. 267–268. M/s Bishen Singh Mahendrapal, New Delhi, India.
Krishnamurthy, V. N., Sudhakar, K.B. and Latha, L. 2014. Preliminary phytochemical and wound healing activity of Cardiospermum helicacabum Linn. Sci. Revs. Chem. Commun. 4(3): 101-108.
Kumar, R., Murugananthan, G., Nandakumar, K., and Talwar, S. 2011. Isolation of anxiolytic principle from ethanolic root extract of Cardiospermum halicacabum. Phytomedicine 18:219–223.
Kumaran, A., and Karunakaran, R.J. 2006. Antioxidant activities of the methanol extract of Cardiospermum halicacabum. Pharmaceutical Biology. 44(2): 146-151.
Manandhar, N.P. and Manandhar, S. 2002. Plants and people of Nepal, Timber Press. 135.
Mat-Salleh, K., and Latiff, A. 2002. Tumbuhan Ubatan Malaysia, Pusat Pengurusan Penyelidikan Universiti Kebangsaan Malaysia, Selangor, 477-478.
Nadkarni, K. M. (1976). Indian Materia Medica. Popular Book Depot, Bombay. 271.
Neill, A.L. and Hunt, N.H. 1992. Pathology of fatal and resolving Plasmodium berghei cerebral malaria in mice. Parasitology. 105: 165–175.
Neuwinger, H.D. African Traditional Medicine: A Dictionary of Plant Use and Applications. Medpharm GmbH Scientific Publishers, Stuttgart, Germany.pp. 1-300:2000.
Otshudi, A.L., Vercruysee, A. and Fotiers, A. 2000. Contribution of the ethnobotanical, phytochemical and pharmacological studies of traditionally used medicinal plants in the treatment of dysentery and diarrhoea in Lomela area (DRC). J Ethnopharmacol. 71: 411-423.
Panda, H.2000. Medicinal Plants Cultivation & Their Uses, Asia Pacific Business Press, India. 512-513.
Rao, N.V., Prakash, K.C. and Kumar S.M. 2006. Pharmacological investigation of Cardiospermum halica-cabum (Linn) in different animal models of diarrhoea. Ind jour of Phar. 38(5): 346-349.
Rao, V.S.N., Santos, F.A., Sobreika, T.T., Souza, M.F., Melo, L.L. and Silveria, E.R.1997. Investigation on the gastroprotective and anti-diarrhoeal properties of ternatin, a tetramethoxyflavone from Egletes viscose. Planta Med. 63: 146-149.
Sadique, J., Chandra, T., Thenmoshi, V., andElango, V. 1987. Biochemical modes of action of Cassia occidentalis and Cardiospermum halicacabum in inflammation. Journal of Ethnopharmacology. 19: 201-212.
Santha Kumari, G., Pillai, N.R., Nair, R.B. 1981. Diuretic activity of Cardiospermum halicacabum L. in rats. Journal of Scientific Research in Plant Medicine. 2(1/2): 32-34.
Satyavathi, G., Raina, M.K., and Sharma, M. 1976. Medicinal Plants of India. Indian Council of Medical Research, New Delhi.
Shareef, H., Rizwani, G.H., Mahmood, S., Khursheed, R. and Zahid, H. 2012. In vitro Antimicrobial and Phytochemical Analysis of Cardiospermum halicacabum L. Pak. J. Bot. 44(5):1677-1680.
Sidigia, I., Nyaigotti-Chacha, C., & Kanunah, M.P. 1990. Traditional Medicine in Africa. East African Educational Publishers, Nairobi.
Srinivas, K., Choudhary, K.A., Rao, S.S., Satyanarayana, T. and Krishna, R.V. 1998. Phytochemical investigation of Cardiospermum halicacabum Linn. Indian J Natural Products. 14: 24-27.
Urdampilleta, J.D., Coulleri, J.P., Ferrucci, M.S., Forni-Martins E.R. 2013. Karyotype evolution and phy-logenetic analyses in the genus Cardiospermum L. (Paullinieae, Sapindaceae). Plant Biol (Stuttg). 15(5):868-881.
Venkatesh Babu, K.C., and Krishna Kumari, S. 2006. Cardiospermum halicacabum suppresses the production of TNF-alpha and nitric oxide by human peripheral blood mononuclear cells. African Journal of Biomedical Research. 9: 95-99.
Waako, P.J., Gumede, B., Smith, P., &Folb, P.I. 2005. The in vitro and in vivo antimalarial activity of Cardiospermum halicacabum L. and Momordica foetida Schumch. Et Thonn. Journal of Ethnopharmacology. 99: 137-143.
Warrier PK 1996. Indian Medicinal Plants.1: 377-379.
Yu, L.L., Liao, J.F., and Chen, C.F. 2000. Anti-diarrhoeal effect of water extracts of Evodiae fructus in mice. J Ethnopharmacol. 73:39-45.
Published
How to Cite
Issue
Section

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright © Author(s) retain the copyright of this article.