Formulation and Evaluation of Tooth Gel from Aloe vera leaves extract


  • Vaibhav Shende Kamla Nehru College of Pharmacy, Butibori, Nagpur 441108, Maharashtra, India
  • Roshan Telrandhe Kamla Nehru College of Pharmacy, Butibori, Nagpur 441108, Maharashtra, India


Aloe vera, leaves extract, tooth gel, dental, anti-microbial, ZOI, herbal


The aimed of current research to formulate tooth gel utilizing leaf extract of Aloe vera. In multiple clinical studies, Aloe vera has used in dentistry for wound-healing effect, gingivitis, plaque control and curing oral mucosal lesions. Aloe vera is natural, ancient ingredient. The formulated Aloe vera tooth gel evaluated by physical examination: Colour-yellowish brown, Appearance-Homogeneous, smooth nature, Transparency-translucent and Relative density-10.5, No microbial growth in sample plate, pH-7.5, Viscosity-3100cp, Extrudability amount percent-91.33, Spreadability-6.5cm/sec and obsereved good stability. The anti-microbial evaluation against Staphylococcus aureus reveal that formulated aloe vera tooth gel exhibited notable activity with ZOI of 19.5 mm at MIC of 25?g/mL. The outcome from this research evidently signified that the natural plant Aloe vera using to formulate tooth gel may be a new approach to formulate tooth gel economically and minimum side effect than synthetic formulation and good scope in future about dental research in natural remedies.


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How to Cite

Vaibhav Shende, and Roshan Telrandhe. “Formulation and Evaluation of Tooth Gel from Aloe Vera Leaves Extract”. International Journal of Pharmaceutics and Drug Analysis, Oct. 2017, pp. 394-8,



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