Bombax ceiba thorn extract mediated synthesis of silver nanoparticles: Evaluation of anti - Staphylococcus aureus activity
Keywords:Bombax ceiba, extract, silver, nanoparticle, biosynthesis, green synthesis
The current research aimed at fabricating plant extract mediated biosynthesized silver nanoparticles (AgNPs) utilizing thorn extract of Bombax ceiba (TEBC). The synthesized AgNPs was characterized by UV spectroscopy where the surface plasmonic resonance peak (SPR) was located at 222 nm. The scanning electron microscopy (SEM) studies demonstrated that the morphology of fabricated nanomaterials was primarily cylindrical of average size of 20-30 nm with some spindles of size >50 nm. The anti-microbial evaluation against Staphylococcus aureus revealed that AgNPs exhibited notable activity with ZOI of 27.2 mm at MIC of 25 ?g/mL. The outcome of this research evidently signified that the biofabricated AgNPs using TEBC may be a new greener approach or technology to formulate anti-bacterial nanodrugs in future.
Telrandhe R. Nanotechnology for cancer therapy: Recent developments. Eur J Pharm Med Res. 2016;3(11): 284-294.
Prabhu S, Poulose EK. Silver nanoparticles: mechanism of antimicrobial action, synthesis, medical applications, and toxicity effects. Int Nano Lett. 2012;2(1): 32-44.
Mittal AK, Chisti Y, Banerjee UC. Synthesis of metallic nanoparticles using plant extracts. Biotechnol Adv. 2013;31(2): 346-56.
Bharti SK, Singh SK. Metal based drugs: Current use and future potential. Der Pharm Lett. 2009;1(2): 39-51.
Ahmed S, Ahmad M, Swami BL, Ikram S. A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: a green expertise. J Adv Res. 2016;7(1): 17-28.
Hajipour MJ, Fromm KM, Ashkarran AA, de Aberasturi DJ, de Larramendi IR, Rojo T, Serpooshan V, Parak WJ, Mahmoudi M. Antibacterial properties of nanoparticles. Trends Biotechnol. 2012;30(10): 499-511.
El-Nour KM, Eftaiha AA, Al-Warthan A, Ammar RA. Synthesis and applications of silver nanoparticles. Arab J Chem. 2010;3(3): 135-40.
Thakkar KN, Mhatre SS, Parikh RY. Biological synthesis of metallic nanoparticles. Nanomed Nanotechnol Biol Med. 2010;6(2): 257-62.
Mahapatra DK, Kumar Bharti S, Asati V. Nature Inspired Green Fabrication Technology for Silver Nanoparticles. Current Nanomed. 2017;7(1): 5-24.
Iravani S. Green synthesis of metal nanoparticles using plants. Green Chem. 2011;13(10): 2638-50.
Chaudhary PH, Khadabadi SS. Bombax ceiba Linn.: pharmacognosy, ethnobotany and phyto-pharmacology. Pharmacog Commun. 2012;2: 2-9.
Kamble MA, Mahapatra DK, Dhabarde DM, Ingole AR. Pharmacognostic and pharmacological studies of Bombax ceiba thorn extract. J Pharm Pharmacog Res. 2017;5(1): 40-54.
Divakar TE, Rao YH. Biological synthesis of silver nano particles by using Bombax ceiba plant. J Chem Pharm Sci. 2017;10(1): 574-576.
Kanhed AA, Mehere AP, Pandey KR, Mahapatra DK. 4-(2-chloroacetamido) Benzoic Acid Derivatives as Local Anesthetic Agents: Design, Synthesis, and Characterization. UK J Pharm Biol. 2016;4(6): 35-44.
Dangre PV, Godbole MD, Ingale PV, Mahapatra DK. Improved dissolution and bioavailability of eprosartan mesylate formulated as solid dispersions using conventional methods. Indian J Pharm Edu Res. 2016;50(3): S209-S217.
Mahapatra D K, Shivhare R S, Joseph T M. Design and Characterization of Murrayanine Linked Isoxazole Derivatives: Novel Class of Bacteriocidal Agents. Int J Res Drug Pharm Sci. 2017;1(1): 11-15.
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