ANTI -HYPERGLYCEMIC EFFECTS ON STEVIA REBAUDIANA ON ALLOXAN INDUCED DIABETIC RATS

Authors

  • M. KALAISELVI Department of Biochemistry, Navarasam Arts and Science College for Women Arachalur, Erode-638101. Tamilnadu

Keywords:

Stevia Rebaudiana, blood glucose, Alloxan, Carbohydrate, Albumin

Abstract

Stevia rebaudiana (Asteraceae) ispopular in the name ‘Sweet tea’ or ‘khaa gee because of its pleasant flavor apart from increasing the sweetness of the product. Traditional medicine accounts for its use externally as anti -inflammatory and internally asanemia and as contraceptive. The aim of the study was to investigate anti hyper glycemic activities ofAqueous leaves extract of Stevia rebaudiana using alloxan induced diabetic rats. Aqueous leaves extract of Stevia rebaudiana was prepared by cold maceration process method. Antihyperglymic activity of the extract was examined by alloxan induced rats with extracts in the concentration of 100 mg/kg body weight (b.w.).The blood was collected from hearts after sacrificing rats. Then the serum was separated by centrifugation at 2500 rpm. The serum was then stored in the refrigerator for 48hrs till the assays were done. The serum was used for the determination of biochemical parameters.  From the results it was observed that the blood glucose sugar level reduced. The aqueous leaves extract Stevia rebaudiana showed significant protection against diabetes.

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Published

2017-08-30
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How to Cite

M. KALAISELVI. “ANTI -HYPERGLYCEMIC EFFECTS ON STEVIA REBAUDIANA ON ALLOXAN INDUCED DIABETIC RATS”. International Journal of Pharmaceutics and Drug Analysis, Aug. 2017, pp. 347-53, https://ijpda.com/index.php/journal/article/view/301.

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