• Neelam swathi Ratnam Institute of Pharmacy, Pidthapolur (V), Muthkur (M), Nellore-524346, Andhra Pradesh, India
  • Yerikala Ramesh Ratnam Institute of Pharmacy, Pidthapolur (V), Muthkur (M), Nellore-524346, Andhra Pradesh, India
  • Manavalan Gobinath Ratnam Institute of Pharmacy, Pidthapolur (V), Muthkur (M), Nellore-524346, Andhra Pradesh, India


Yellow fever, zika virus, Aedes Aegypti Mosquito, Vaccines


Yellow fever is one of the viral hemorrhagic fevers widely spreading in the major parts of Africa,   American, and Europe continents. Yellow fever is the most dangerous disease because it is responsible for lakhs of death of people approximately more than 2,00,000  annually. Aedes mosquitoes acts as a vector for rapid transmission of yellow fever as it carries yellow fever virus and injected into host for replication of virus. Severe  symptoms noticed in patients who are suffering from yellow fever includes severe  headache, high fever, low pulse, jaundice, hematemesis, chills, and hepatic necrosis. The infection of yellow fever virus occurs in two forms i.e urban cycle and sylvatic cycle. Unlike zika and other viruses yellow fever virus having an advantage effective vaccination is available for it. Vaccination acts very effectively in reducing  the mortality rate upto 85%. Vaccine provides life long immunity against the yellow fever virus and even booster dose is not needed for it. Vaccination provided compulsory to the people who are travelling from epidemic areas to other countries.  There is no risk of yellow fever in asia but recently china imported 6 cases of yellow fever accidentally. India is one of the most favourable place  for rapid transmission of yellow fever because aedes aegypti mosquitoes responsible for wide spread of disease is much more in abundance. But till now none of the cases with yellow fever is reported in india. In future if yellow fever unfortunately enters india it destroys the huge population within short period of time before vaccine stocks are delivered.


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How to Cite

Neelam swathi, Yerikala Ramesh, and Manavalan Gobinath. “A REVIEW ON YELLOW FEVER”. International Journal of Pharmaceutics and Drug Analysis, vol. 4, no. 12, Dec. 2016, pp. 514-21, https://ijpda.com/index.php/journal/article/view/260.



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