CONTRIBUTION OF NON-PHARMACOLOGICAL FACTORS IN NON-COMPLIANCE OF DOTS AMONGST TUBERCULOSIS PATIENTS

Authors

  • Md Salahuddin Ansari College of Pharmacy Aldawadmi. Shaqra University, KSA
  • Abdulmohsen H. AlRohaimi College of Pharmacy Aldawadmi. Shaqra University, KSA
  • Khalid U Khayyam Department of Public Health and Respiratory Disease, LRS Institute of Tuberculosis and Respiratory Disease, Sri Aurbindo Marg, New Delhi (India)
  • Manju Sharma Department of Pharmacology, Jamia Hamdard, New Delhi (India)
  • Md Sarfaraz Alam Department of Pharmaceutics, College of Pharmacy, Jizan University, KSA

Keywords:

Tuberculosis, Non-Compliance, Psychological Factors, Personal Factors and Directly observed treatment short course

Abstract

Background: One of the important factors in control of tuberculosis is non-compliance has role in multi-drug resistant tuberculosis, poor treatment outcome and cause increased morbidity and mortality of tuberculosis.

Objective: This study explores the contribution of non-pharmacological factors in non-compliance of directly observed treatment short course among tuberculosis patients.

Methodology: The Cross sectional prospective study was interviewed by using set of questionnaire with enrolled patients of TB at DOTS centre of LRS Institute of Tuberculosis and Respiratory disease New Delhi, India. The Patients who discontinue and interrupted treatment for more than 2 months were categorized as noncompliance cases.

Results: Five hundred sixty six patients TB patients enrolled during the study out of which forty non-compliance cases we observed. various factors and their contribution in noncompliance, the nuclear family have contribution 40 %, living life style of three member family in one room set contribute 42.5% role in non-compliance and types of patients who was new found 35% contribution in non-compliance. Beside these 10% of non-compliance TB patient have positive influence to tuberculosis treatment, as family and social factors have 70 % negative influence in non-compliance as well as psychological and their positive influence to non-compliance in tuberculosis treatment were only 40%.

Conclusion: Various factors contribute in non-compliance of tuberculosis treatment therefore more attention should be paid to psychological aspect in order to behavioral and life style modification during tuberculosis treatments.

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Published

2016-10-10
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Md Salahuddin Ansari, Abdulmohsen H. AlRohaimi, Khalid U Khayyam, Manju Sharma, and Md Sarfaraz Alam. “CONTRIBUTION OF NON-PHARMACOLOGICAL FACTORS IN NON-COMPLIANCE OF DOTS AMONGST TUBERCULOSIS PATIENTS”. International Journal of Pharmaceutics and Drug Analysis, vol. 4, no. 10, Oct. 2016, pp. 452-9, https://ijpda.com/index.php/journal/article/view/252.

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