In vitro Free Radical Scavenging Activity, Phytochemical Screening and Quantitative Analysis of Passiflora ligularis Seed
Keywords:Tenofovir, Emtricitabine, Simultaneous Estimation, Validation, HPLC
The medicinal properties of plants are due to the presence of chemical substances that produce certain definite physiological action on the human body. The qualitative analysis as well as quantification of phytochemicals of a medicinal plant is regarded as fundamental step in any kind of medicinal plant research. Ethanolic extract of Passiflora ligularis seed was screened for secondary metabolites such as flavonoids, tannins and carbohydrates. Total alkaloid, flavonoid, phenol, saponin and tannin contents were also analysed quantitatively. The preliminary phytochemical screening revealed presence of flavonoids, saponins, tannins, phenols and glycosides. Analysis of the free radical scavenging activity of the extract exposed a concentration dependent antiradical activity resulting from the reduction of radicals to non-radical forms. Findings of the study provided support that crude extract of the plant species contains medicinally important bioactive compounds and justify the use of the plant in the traditional medicine for the treatment of different diseases.
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