Retrospective Study on Diabetes Patients in two different regions in Oman

Authors

  • Khoula Abdullah Issa AL-Habsi Oman Medical College, Pharmacy department, Muscat, Sultanate of Oman.
  • Hameeda Nasser Saif AL-Mahdouri Oman Medical College, Pharmacy department, Muscat, Sultanate of Oman.
  • Dr.Nirmala Amaresh Oman Medical College, Pharmacy department, Muscat, Sultanate of Oman.
  • Dr.AR.Mullaicharam Oman Medical College, Pharmacy department, Muscat, Sultanate of Oman.

Keywords:

Type 1 diabetes mellitus, Type 2 diabetes mellitus, prevalence, medication management

Abstract

Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin
action or both. The number of people with diabetes in increasing due to population growth, aging , urbanization and
increasing prevalence of obesity and physical inactivity. Aim: The aim of this study is to assess different lines of
medications prescribed and combination therapy on diabetes management and also to assess the most common associated
disease with diabetes in two hospitals in different regions. Materials and Methods: A retrospective study was conducted
based on 100 prescription (from Jan to June 2013) collected randomly for type 1 and type 2 diabetic patients from AL
Rustaq hospital and Sinaw hospital in Oman. Prescriptions were classified into two groups according to the type of diabetes
studied (T1DM and T2MD). Patients, Age, Gender, diseases associated and medication used were noted. Results: A high
prevalence of diabetes was observed in T2DM (with 99%) while T1DM about 1% in AL-Rustaq and Sinaw hospital. In
T2DM, Metformin is the most prescribed drug followed by Gliclazide as monotherapy in AL-Rustaq hospital. The most
prescribed medicine use as monotherapy is metformin (72%) followed by Gliclazide (18%) then glibincamide (10%) in
SinawhospitalIn combination therapy, metformin+glibenclamide followed by metformin+gliclazide were the most
commonly prescribed in AL-Rustaq hospital. In Sinaw hospital the combination therapy in which metformin plus
glibincamide is the most common (53%). Then metformin plus gliclazide(32%), followed by metformin plus gliclazide
plus Insulin(N) (5%), then metformin plus glibincamide plus Insulin(N)(4%) then insulin plus oral hypoglycemic(3%)
then insulin(N) plus insulin(R) plus gliclazide(2%) then Metformin plus Insulin(N) plus Insulin (R)(1%). Nearly 50%
Males and 50% females having diabetes was in both hospitals. Maximum patients with DM were of the age group (40-49)
years. Dyslipidemia is the most common associated disease with diabetes in AL-Rustaq hospital In Sinaw hospital, the
majority of the patients are having hypertension as associated disease (49%), then came coronary heart disease (32%) then
dyslipidemia (19%). there are other associated diseases but in limited percentage such as nephropathy, retinopathy,
neuropathy, etc.Conclusion: In this study prevalence of T2DM was more. Diabetes was found to be in age group (40-49) in
AL-Rustaq hospital. This study shows that both genders have same proportion.

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Published

2015-04-16
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How to Cite

Khoula Abdullah Issa AL-Habsi, Hameeda Nasser Saif AL-Mahdouri, Dr.Nirmala Amaresh, and Dr.AR.Mullaicharam. “Retrospective Study on Diabetes Patients in Two Different Regions in Oman”. International Journal of Pharmaceutics and Drug Analysis, vol. 3, no. 4, Apr. 2015, pp. 91-97, https://ijpda.com/index.php/journal/article/view/148.

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Research Articles
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