Formulation, Standardization and Comparative Evaluation of Ancient Nanomedicine Varatika Bhasma

Authors

  • VAKTE MONALI B Sanjivani College of Pharmaceutical Education and Research, Sahajanandanagar, Kopargaon Dist. Ahmadnagar, Pin. 423603
  • PANDE VISHAL V Sanjivani College of Pharmaceutical Education and Research, Sahajanandanagar, Kopargaon Dist. Ahmadnagar, Pin. 423603
  • PAWAR SARITA S Sanjivani College of Pharmaceutical Education and Research, Sahajanandanagar, Kopargaon Dist. Ahmadnagar, Pin. 423603

Keywords:

Varatika, bhasma, Standardization, Ayurveda

Abstract

Bhasmas are unique Ayurvedic metallic/mineral preparations with herbal juices, widely recommended to treat variety of
chronic ailments. Varatika bhasma is a traditional Ayurvedic medicinal preparation, used for protection against ulcers.
Varatika is external shell of sea animal Cypreamonetalinn. Chemically varatika is identified as carbonate of calcium. In the
present research an attempt has been made to carry out a comparative standardization of formulated varatika bhasma (VB1)
prepared as per standard classical methods and marketed Varatika bhasma(VB2). These formulations where evaluated for
physical properties, chemical characterization using sophisticated instrumentation techniques such as particle size, AAS,
SEM, XRD. Physico-chemical standards where determined for both the samples.The X-ray Diffraction analysis of both
formulations exhibited crystalline nature and nano-sized particles. In SEM study of VB2 shows well-defined fibre like
structures while VB1 shows relatively compact microcrystalline aggregates with loss of grain boundaries.

Downloads

Download data is not yet available.

References

Frew AJ: Allergen immunotherapy. J Allergy Clin

Immunol 2010, 125:S306-313.

Kaplan AG, Balter MS, Bell AD, Kim H, McIvor

RA: Diagnosis of asthma in adults.

CMAJ 2009, 181:E210-E220.

Kovesi T, Schuh S, Spier S, Bérubé D, Carr S,

Watson W, McIvor RA: Achieving

control of asthma in preschoolers. CMAJ 2010,

:E172-E183.

Global Initiative for Asthma (GINA): Global strategy

for asthma management and prevention.2009.

Lemanske RF, Busse WW: Asthma: Clinical

expression and molecular mechanisms.

J Allergy Clin Immunol 2010, 125:S95-102.

McFadden ER Jr. A century of asthma. Am J Respir

Crit Care Med. 2004;170(3):215–221.

Wardlaw AJ, Brightling C, Green R, Woltmann G,

Pavord I. Eosinophils in asthma and other allergic

diseases. Br Med Bull. 2000;56(4):985–1003.

Djukanovic R, Homeyard S, Gratziou C, et al. The

effect of treatment with oral corticosteroids on

asthma symptoms and airway inflammation. Am J

Respir Crit Care Med. 1997;155(3):826– 832.

ten Brinke A, Zwinderman AH, Sterk PJ, Rabe KF,

Bel EH. “Refractory”eosinophilic airway

inflammation in severe asthma: effect of parenteral

corticosteroids. Am J Respir Crit Care

Med.2004;170(6):601–605.

O’Byrne PM, Pedersen S, Lamm CJ, Tan WC, Busse

WW. Severe exacerbations and decline in lung

function in asthma. Am J Respir Crit Care Med.

;179(1):19–24.

Bousquet J, Bousquet PJ, Godard P, Daures JP. The

public health implications of asthma. Bull World

Health Organ. 2005;83(7):548–554.

Asthma UK. High cost of asthma in West Midlands.

Available from:

http:// www.asthma.org.uk/ news_media/

media_releases/ high_cost_of_ asthm_3.html.

Updated 2009 Oct 22.

Published

2015-04-28
Statistics
4 Views | 10 Downloads
Citatons

How to Cite

VAKTE MONALI B, PANDE VISHAL V, and PAWAR SARITA S. “Formulation, Standardization and Comparative Evaluation of Ancient Nanomedicine Varatika Bhasma”. International Journal of Pharmaceutics and Drug Analysis, vol. 3, no. 4, Apr. 2015, pp. 126-33, https://ijpda.com/index.php/journal/article/view/144.

Issue

Section

Research Articles
Share |