ISSN : 2348 - 8948

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Volume : 6 Issue :2 Month : February (2018)
Page Numbers : 122-126

Cytogenetic Screening in Colorectal Cancer Patients of Tamil Nadu Population

Padma M, Nimmisha. E, Sasikala P, Dhivya.V, Balachandar.V, Ganesan.S, *
Colorectal cancer (CRC) is one of the most com-mon types of cancer worldwide and harbors dis-tinct chromosomal alterations. This study tries to investigate clinic-pathological, chromosomal alterations to identify the novel genes and expression pattern in Tamil Nadu population of CRC patients. Patients with CRC (n= 13) and healthy controls (n= 13) were evaluated by analyzing the chromosomal alterations by standard protocols. Higher percentage of deletions was found with 46, XY, del 18p- and translocation was 46, XY. In conclusion, corre-lation of focal chromosomal alterations enriched in cancer genes with its clinical outcome indicates a prognostic index contributing to drive the process of CRC.
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