ISSN : 2348 - 8948

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Volume : 6 Issue :2 Month : February (2018)
Page Numbers : 105-115

Formulation and Evaluation of Oral Fast Dissolving Film of Bisoprolol Fumarate

Somesh Bawane, Roshan Telrandhe*, Dr. S. D. Pande
The present work aimed to prepare fast dissolving film of bisoprolol fumarate with the reason of developing a dosage from, for a very fast onset of action, the film were prepared by solvent casting method with polymers. The compatibility study between drug and physical mixture was performed by FT-IR. The film were characterized for various physicochemical properties such as, physical appearance-Transparent, surface texture, weight uniformity, thickness, folding endurance, disintegration time, tensile strength, % elongation, drug content, in-vitro drug release study, SEM Study shows smooth surface and Stability study indicate the good observation. All parameter shows better results. A marked increase in the disintegration time was exhibited by fast dissolving time formulation. The fast dissolving film of bisoprolol fumarate can be considered suitable for clinical use. The prepared film proved to be potential candidate for safe and effective fast dissolving drug delivery.
 
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