ISSN : 2348 - 8948

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Volume : 6 Issue :1 Month : January (2018)
Page Numbers : 29-34

Comparitive In-Vitro Evaluation Of Commercially Available Generic And Branded Propranolol Hydrochloride Immediate Release Tablets

M Gayathri Devi*, M Savithri, P Uma Devi, B Nagamani, PV Madhavi Latha, Y Tarakeswar Rao, V Mounika
The present work describes about the comparative in-vitro study of commercially available generic and branded Propranolol Hydrochloride tablets. The generic and branded Propranolol hydrochloride tablets were taken and evaluated for different parameters like weight variation, hardness, friability, disintegration, percentage purity and dissolution studies. According to USFDA, generic drugs are identical and are within the acceptable bioequivalent range to the brand-name counterpart with respect to pharmacokinetic and pharmacodynamic properties. Generics are almost identical to that of branded drugs which are 80% cheaper on average. The generic drugs of various pharmaceutical companies are sold at low cost and are checked for their therapeutic efficacy by comparing with that of branded ones. The in-vitro results of both generic and branded were compared and found to be within the limits and claimed that generics are almost equal to branded drugs in all aspects except cost.
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